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paleness bremelanotide (sex drug)

 Bremelanontide makes lab mammals have sex 7x times as often. People say it works on them. Make a two peptide version that makes the body pale, while the sex version crosses the blood brain barrier. The person becomes paler as they become sexier
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Bremelanotide (also known as melan-o-tan) causes lab mammals to have sex 7 times as often. The thing is, that at humans it upregulates melanin production causing an imitation suntan.

I think that attaching a polyglycine above 400 amu to bremelanotide would keep it on the body side of the blood brain barrier, while fully occupying bodyside receptors. It would be a slightly modified version so as to be inactive or even possibly block endogenous tanning - making the person paler.

Meanwhile the regular bremelanotide would reach the brain, causing sexiness. The person becomes paler while their sex drive goes up.

—beanangel, Jul 29 2017

Glutathione Skin Lightening. http://www.bmj.com/.../354/bmj.i4386.long
[bs0u0155, Aug 01 2017]

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       Well, in this year it only could have been one of a couple of people.   

       And it's in an appropriate category.
—normzone, Jul 29 2017
   

       I knew there was a reason blondes have more fun...
—RayfordSteele, Jul 30 2017
   

       My question exactly [Ian Tindale]!!And also, 7 times more often than what...rabbits?
—xandram, Jul 31 2017
   

       Maybe they have sex seven times as often because it makes them enjoy it less and they're wistfully trying to hit the spot.
—nineteenthly, Jul 31 2017
   

       Don't let my wife see this page.
—RayfordSteele, Jul 31 2017
   

       Also, what's with the paleness? Who (apart from Michael Jackson, who I believe has left the stage) wants to be paler?
—MaxwellBuchanan, Jul 31 2017
   

       I want to be paler - it's on my bucket list.
—AusCan531, Jul 31 2017
   

       Pandas are mostly white, but sex hasn't worked out well for them.
—MaxwellBuchanan, Jul 31 2017
   

       Maybe try some of this chemistry magic on them?
—RayfordSteele, Jul 31 2017
   

       My brain has been too thoroughly infested by my daughter's constant Homestuck references to post anything remotely resembling a sensible reply about an idea that combines sex and paleness.   

       Especially since @AusCan531 has now brought a bucket into the discussion.
—prufrax, Aug 01 2017
   

       //Who (apart from Michael Jackson, who I believe has left the stage) wants to be paler?//   

       Essentially everybody, and there's big money in it <link>. Many use glutathione, either topically, I.V. or by swallowing the stuff. It looks pretty interesting, and all over the place theoretically. Other compounds used include vitamin c and hydroquinone. The proposed mechanisms are all in the "we think they're acting as anti oxidants" camp, which is on shaky ground. Mainly since if applied topically, they'll oxidize in air. It looks like there's some interesting redox chemistry going on with the 3 melanin subtypes that revolves around cycling intermediates, which makes more sense.   

       Also, as it turns out, melanin is synthesized from tyrosine. A few rudimentary calculations show that induction of rapid whole body melanin synthesis, combined with a protein-poor diet easily depletes the circulating concentrations of tyrosine/l-dopa. That might well reduce the ability to synthesize dopamine, at least transiently, supporting the idea of a sun-induced ADHD type thing.   

       This is the best explanation so far for certain behavior during a thankfully undocumented Spanish drinking holiday that may or may not have happened in the summer of 2001.
—bs0u0155, Aug 01 2017
   


 

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