h a l f b a k e r yAssume a hemispherical cow.
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This is an excellent idea. Admittedly, you'd have to find a way to stop the peptides being digested by the proteases in most current washing powders; and then you'd have to find a completely original way to make peptides migrate through your skin; and also have to regulate washing powders in the same way that the drugs themselves would be regulated. But, other than that, there are only a few additional problems. |
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Ah, hang on. The statement "peptide drugs are effective at micrograms or less" is for the most part wrong, with a very, very few exceptions. It's also worth noting that mice are considerably smaller than humans, so even epithalon would need to be delivered in tens-of-milligram quantities to achieve the same concentration. But other than that, no problems. |
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And what Ian said. It's just irritating. |
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Ditto on what Max and Ian said. |
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Wouldn't most active peptides be locally acting so small amounts would be normal? The biggest problem here being the galactic travel and survival ability from undies to target cell machinery. |
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Maybe via nose capillaries then there would be a good reason to sniff undies. |
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Leads one to wonder how many household products are laced with skin-absorptive addictive substances. |
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I thought skin was pretty much impermeable - isn't
that largely the whole point of skin? If skin was
easily permeable you'd drown in the shower. |
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//I thought skin was pretty much impermeable// Some things will perm it. You can always add DMSO to stuff - makes skin permeable to a good number of things. |
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"" One possible contact peptide is AEDG, epitalon, which prevents cancers (among these breast cancer) in mice and makes them live longer. "" |
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Can you put the AEDG in a spray can ? Or maybe aerosol ? |
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That would make it easier to get the stuff on the tiny bras that mice wear. |
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----
I got in the habit of duplicating the summary in the first paragraph, because spellcheck doesn't work on the summary part at least in my hopeless old computer. So I won't do that as much, but I am still a hopeless speller. And would just drive past any Halfbakery spelling bee. |
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actually some peptides are used to hasten the transport of drugs at the dermis. [link] so a couple peptides might be better. |
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Ah, that explains all the Tide commercials then. |
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//some peptides are used to hasten the transport of drugs at the dermis// Yes, but it's no good transporting them at the dermis. They need to go through the epidermis and also through the dermis, if they're supposed to be having a systemic effect. |
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