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What to do about pill overdoses?
Make the surface of the pills very slightly emetic (vomit
inducing)
You can imagine a technology where a 1/100th dose of an
emetic is at the surface of each pill. If you take more than
50, you have a 50% chance of vomiting what you took.
If you take 100,
you have a 100% chance of vomiting.
Vomiting of course removes 40-90% of the oral dose of the
pill.
Baked and patented
https://www.google.com/patents/US9060950
It's enough to make you sick. [MaxwellBuchanan, Jan 15 2018]
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Annotation:
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The strange thing, [beany], is that this is not such a stupid idea. |
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Yes, nice idea but a slight emetic might create subtle effects which may be contra to the active ingredient's goal. |
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[Ian] 2 out of 10. Needed more, such as wearing too many coats can make you sick. |
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Any possibility of making a binary emetic? Then make half
of the pills have one of the components, while the others
have the second component. The pills should be visually
indistinguishable. If you take one, it has no emetic effect.
If you take two, there is a 50% chance of getting both
components and inducing vomiting. |
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What if the tablets are anti-nauseants ? |
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//Any possibility of making a binary emetic?
Then make half of the pills have one of the
components, while the others have the second
component.// |
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Was just about to write that. Darn! |
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I like this better than having something that might
make you slightly sick with a regular dosage, since
it seems like a regular dosage with a little bit of
the vomity stuff would cause a little stomach
upset. This would be a way to make the person
violently ill with anything over a couple of pills. |
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For many (but not all) medicines, the dangerous dose is many times the maximum prescribed dose. I think a weak emetic might work in many cases. Paracetamol would be difficult, though, because doses above 10g can be dangerous, whilst many people take 1-3g per day to manage pain. |
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//If you take more than 50, you have a 50% chance of vomiting what you took. |
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If you take 100, you have a 100% chance of vomiting.// |
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That's not how odds work. |
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One could always put a sub-critical mass of a suitable isotope in each pill. |
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The isotope with the smallest critical mass your primitive human
science knows of is californium-252, with a critical mass of
2.73kg for an isotropic bare sphere, and a half-life of 2.6 Earth
years. |
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Any other brilliant insights ... ? |
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Clearly, the borg are not yet familiar with elements in the Third Sea of Stability. |
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Any other brilliant insights ... ? |
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You're turning this into a pantomime... |
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//Oh Yes We Are// Oh no you're not. |
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// Sp. "Borg"// My apologies; I'm used to typing the lowercase version, as in "suborganization". |
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//Observe, O link, up there!// That makes no grammatical sense whatsoeveratall. Moreovermore, the link itself seems to be unrelevant. |
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//it seems like a regular dosage with a little bit of the vomity stuff would cause a little stomach upset// Alcohol and salt are convenient counterexamples. However, regarding binary emetics, you would probably want (a) a pro-emetic that was inactive but capable of being converted into a strong emetic and (b) an acid-tolerant enzyme that performed the necessary conversion. |
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Omnes: "OH YES YOU ARE !" |
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// (a) a pro-emetic that was inactive but capable of being converted into a strong emetic and (b) an acid-tolerant enzyme that performed the necessary conversion. // |
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There's got to be a better way ... |
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// There's got to be a better way ...// Well, there's an *other* way... bet there's not too many overdoses from suppositories. In keeping with the idea, a light coating of Propulsid - which does pretty much what it says - would be effective. |
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// not too many overdoses from suppositories. // |
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Apart from the notorious "sherry enema" incident … |
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// "Sherry Enema"// isn't she Donald Trump's foreign policy advisor? |
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No, she was Bill Clinton's "personal assistant" ... |
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See <link> "This invention provides capsules containing an emetic, which capsules can encapsulate a drug, wherein the amount of emetic and the amount of drug is such that the number of capsules needed to be ingested to cause emesis is fewer than the number of capsules needed to be ingested to cause overdose of the drug, so that if a person takes an overdose of the emetic encapsulated drug, he or she will vomit before the drug is absorbed by the body." |
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[mb] Thanks. It is always better to have
something useful already exist. I appreciate the look-up.
The patent says "Between 1970 and 2000, some 131,000
people died by accidental drug overdose" I doubt it but
maybe I will think of some other thing. As far as I know
[scad mientist]'s idea is still new. |
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Useful? My understanding of that which constituted a halfbaked idea is clearly out of step. Can we quickly return to "trained hamsters skating in formation on frozen custard" type of idea? |
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Trained xhamsters skating on custard... almost lurid, yet
still absurd. |
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Also, thinking up the cute ones is harder...
Now I'm onto double layer pantiliners. |
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// Baked and Patented // I'd call that patented, but I see
no evidence that someone has actually baked this idea,
either experimentally or for mass consumption. This HB
idea should definitely not be deleted to encourage
someone to actually bake this idea (assuming it actually
turns out to be a good idea when baked). It sounds like
the patented idea actually considers this idea to be prior
art: //U.S. Pat. Nos. 4,175,119 and 4,529,583, herein
incorporated by reference, disclose a medicinal
composition whereby a tablet or capsule is coated with
an emetic to prevent accidental or purposeful drug
overdose. However, this requires the use of coating
machines which health care professionals may not have
access to.// |
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The linked patent is a standard capsule in which many
different drugs could be delivered. The capsule could be
effective against accidental overdose, and might be
easier to roll out to multiple drug manufacturers, but
would not seem to be effective against preventing
intentional overdose if someone was aware of the emetic
capsule and could empty the drugs out of the capsules. |
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Don’t prescribe as a remedy to bulimia. |
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