h a l f b a k e r yThe leaning tower of Piezo
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antibodies (and the active glomming part known as
aptamers)
preferentially attach to various proteins and chemicals.
Linking one side of an antibody to white material, and
the
glomming area to tooth surface chemicals causes white
material to accumulate on the teeth with a new
toothpaste.
This
combination gradually causes the teeth to be
reversibly
painted white, resulting in a whiter smile.
There is also the possibility that milk proteins or
peptides, and even (vaguely) ion exchange resins
could be used instead of expensive antibodies. I think
antibodies might be a go at the dentists office though.
(another three GSK ideas a day production)
Glaxo smith kline is soliciting consumer products ideas
https://innovation....deas/submit-an-idea
[beanangel, Dec 24 2017]
[link]
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If antibodies can grip the surface of teeth then that suggests that it
might be possible to vaccinate against tooth formation. |
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I have no idea why anyone might want to do this. |
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Strictly speaking, aptamers are not the business ends of antibodies. The binding portions of antibodies are sometimes known as CDRs (complementarity determining regions); mini-antibodies can be made which contain only these portions plus a minimal scaffold (this was the basis of the company Domantis). |
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Aptamers are normally DNA, RNA or modified DNA/RNA, selected to have specificities similar to antibodies. Aptamers can also be peptides, but this is an unusual use of the word. Aptamers typically have lower affinities and higher off-rates than antibodies. |
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A new type of furry feeling. |
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Does the word "glom" lose its savour on the bedpost overnight? |
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