h a l f b a k e r yWhy did I think of that?
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Instead of organ donation, an option to donate the decelluarized matrix of your organs. Turns out when you take tissue and kill the cells only and leave the extracellular matrix behind, stem cells reseeded onto the matrix can reform functional organs. By storing the matrix instead of organs themselves,
you can get rid of the "rush to patient" time component altogether. Even if the technology is not quite there yet for some organs, you can start storing the matrix for perhaps the day when we figure out what will work. Also, this may be alot psychologically easier for people or their families to deal with as it is only "non-alive" templates of the organs being reseeded with the cells of the living person.
Stem cell seeded trachea implant
http://abcnews.go.c...t/story?id=15354809 [leinypoo13, Sep 21 2012]
New kidney from matrix
http://www.sciencen...ansplanted_into_rat Just saying. [leinypoo13, Apr 21 2013]
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Annotation:
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Good for bone, and for cartilaginous bits like
tracheae and heart valves maybe. Not sure that
livers or kidneys have matrices... |
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Indeed they do, so do lungs, corneas, arteries and veins.
Pretty sure that every tissue has ECM. It is basically a mix
of proteins, glycosaminoglycans and hyularanon secreted by
cells as they take up residence. It's very interesting how
clearly determinative it is for cellular differentiation as
opposed to the traditional genetic or epigenetic view. |
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I hope this reloaded matrix is less pretentious than
the one with Keanu Reeves. |
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