h a l f b a k e r yBirth of a Notion.
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Researchers recently created a functioning heart in the laboratory. They got an old heart, used detergents to remove the original cells (leaving the extracellular matrix as a framework), and introduced cardiac stem cells which grew to fill the framework.
I want to do the same thing, except for leather
jackets. Skin tissue could be grown on a jacket mold using skin stem cells. To create the mold, you strip the upper-body skin tissue of a recently-dead body (down to the fat) that used to share your clothing measurements.
Next, you remove the original cells with a detergent, leaving the cellular matrix. Then, you introduce your own skin stem cells into the framework, submerge the whole thing in a nutrient-rich bath, and wait.
When it's done, you can keep it alive while wearing it either by hooking its circulation system up to yours through a few intravenous tubes, or by hooking it to some kind of mechanical circulatory pump.
It should act like a another layer of skin. If it gets hot, it'll sweat. Its hair will grow. If it's cut, it will heal and develop a scar. If you start wearing it while you're little, it'll grow with you as your growth stretches it.
By the way, I'm a size S. Anybody size S too?
Lab heart
http://www1.umn.edu...art_in_the_lab.html Researchers create a new heart in the lab [plasticspoon, Mar 12 2009]
Bioengineering organs
http://www.scienced...02/080216095724.htm Culture methods [plasticspoon, Mar 12 2009]
Stem-cell skin grafts
http://www.lifesite...5/feb/05021806.html [plasticspoon, Mar 12 2009]
something like this
Self_20Leather [FlyingToaster, Mar 12 2009]
[link]
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How many additional layers of these things is optimal? One might offer one or two to new and easily offended halfbakers. |
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Let me check my Extreme Skin-O-Meter. |
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In Harry Harrison's Eden trilogy, the sentient bipedal dinosaurs used living animals called 'clokes' to wrap around themselves and keep themselves warm. |
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//Then, you introduce your own skin stem cells into the framework, submerge the whole thing in a nutrient-rich bath, and wait.// |
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Yup. It'll share your DNA. I guess this makes it a bespoke jacket. |
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"Terminators are made up of living tissue over metal endoskeletons..." and strangely, |
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"It rubs the lotion on its skin..." |
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//Your *own* skin cells?// [2fries] has a point, surely celebrity jackets would be more popular. |
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Right, I guess you would want DNA from somebody with nice skin. I wouldn't pay for a jacket that sweats constantly and gets pimples. |
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That makes it preheated, not baked. |
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//That makes it preheated, not baked// Yes, but the Star Wars films (and I assume by extension, the books) are set in a galaxy "a long time ago", so that makes them...no, wait. |
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You can tattoo it too, right? Hmm, I'll stay neutral. |
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// intracellular matrix// Sp. extracellular matrix. |
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//intracellular matrix// Sp. or Df.=Definition .
Definition really shouldn't be confused with
spelling unless your joking. |
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How about a magnetic extracellular matrix with a
intracellular effect. |
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'Excession' by Iain M. Banks relates this very idea. The skin/DNA samples were donated 2 years before then grown and tailored to produce a full suit made of the users skin. |
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IMB never said the matrix was from someone else, and i think the assumption is that it's grown with your own skin. I don't think skin is the best choice because it relies on a circulation, and at the point it's in the bath, that's not there, so it's only going to survive if it's in a very thin layer. I don't think the accessory structures would grow on their own either. There needs to be a layer on the outside to keep it from dehydrating and it could kill you if it gets infected - it could become devastatingly pussy and like von Zumbusch psoriasis, which involves the loss of protein and electrolytes and can be fatal. What might work, i think, are thin layers of corneal epithelium drenched constantly in artificial tears or a jacket made of some form of skin cancer cell. I think the former is more likely, as carcinoma cells tend not to stick together very well. |
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I really think you're going to have to forget about the circulatory system being involved as you'd probably just get shock and dehydration. |
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So this is to create an expensive hairy smelly jacket that makes you look like a fat shirtless guy with a MASSIVE heart surgery scar down the front. Hmmm, I'll give it (+) for originality and a (-) for usability. |
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I am, however, wondering if you could use implants to create skinflaps, or maybe weights and piercings, or...this is starting to seem familiar. |
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For different colors, put it in a tanning booth. |
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//you could use implants to create skinflaps// You don't need to create him - he already exists. |
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As a motorbicycleist I prefer the thing I fall on to be dead and feel no pain. Unlike me. ARRGGGG. [-] |
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Its a lot easier to skin a cow and cure it, and we eat so much beef in the western world, leather is really a waste product that needs using up. |
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It's hard to say which is the by-product. There's beef, leather, dairy, veal and horn, and i imagine pharmaceuticals. Is taurine actually gotten from cows, synthesised or from somewhere else? What's the biggest market and the biggest profit margin? |
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//I prefer the thing I fall on to be dead and feel no pain// |
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Then I reccomend you ride on asphault. What the hell are roads made out of in England anyway? |
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You've designed Hannibal Lecter's wardrobe. |
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up_on_cloud_nine, how do you survive if you don't eat anything? |
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Mike, the roads in England consist of diesel, cow poo, loose stones and holes. |
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