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High levels of cortisol have been noted in some small
children
institutionalized at a critical stage in their mental
development. Small doses of Ketoconazol, a cortisol
inhibitor, may alleviate symptoms.
Any cortisol inhibitor may be a possible pharmaceutical
prophylaxis for high cortisol
levels (in institutional
setting or orphanage, especially). The purpose would be
to prevent reactive attachment disorder—common in
children who were left in orphanages too long; they have
trouble with disruptive behavior–the current solution is to
“create safety” through therapy for adopted children
well after the disorder is diagnosed...rather than prevent
or blunt the levels of the stressor hormone which is
causing the problem. Which is not to say talk therapy
isn't powerful...it just takes so long, and has to be done
after the fact. Yeah, happy foster homes are what you
want. Ketoconazol, and drugs like it, are what you
(potentially might) use when you have 700 kids crammed
into a converted railway barn, eating and sleeping in
shifts...
Psychiatry Watch
http://psychiatry.j...ent/full/2002/425/1
Article on cortisol effects [cloudface, Sep 09 2010]
[link]
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What's the chances anyone on here knows enough about this subject to make any kind of intelligent comment on the mechanism of the idea? |
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I will, however, award a fishbone on the general principal of institutional use of drugs. The administration of Lithium and electroconvulsive therapy probably seemed like good ideas at the time. |
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They still do, for some subjects ... |
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what [Twizz] said. happy foster homes might be a better alternative. |
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[ ] I imagine familial separation to be quite traumatic in a child: in an adult that might require a temporary regimen of anti-depressants. |
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[ ] also. I'm not sure it would work, but it's not right to bone
this on the basis that kids shouldn't be institutionalised in
the first place. Some are, and this just seeks to minimize
the damage. |
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I honestly just assumed this was some kind of spam which had gotten through by mistake! You mean this is an actual serious idea? Are you sure? |
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Interesting though, and as someone who had to deal with that crap as a kid it's nice to see the medical community taking an interest.
They sure didn't back then. |
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One anxiously neurotic bun for you. |
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I haven't the faintest clue so here's a bun. |
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Cortisol is a stress hormone and the problem is not its excess but the situation that produces the stress. I am skeptical that this sort of cortisol excess produces damage. |
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Cortisol excess in Cushings syndrome can produce damage. Ketoconazole can help with that. |
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What [bungston] said. Cortisol's a marker for stress, even
emotional stress. With this sort of correlation, you don't
know if cortisol's part of the problem, or part of the solution,
or, as often happens, a good thing in just the right quantity,
but bad in excess. That cortisol stress reaction is supposed
to be a part of what keeps dominant male
chimpanzees in their high-status positions. But perhaps the
high-status chimps all die young of apoplexy or something, I
dunno. |
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oh, dog, that is a big "maybe". I would postulate "maybe not". If you want to torture some rats and find out then I'm not going to protest. On the other hand sounds like the unhealthy levels of stress are the problem and cortisol (-cue Mentos music- "the stress maker") is a natural and healthy response. |
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[zen_tom] Perhaps a retrospective study of institutionalized
asthmatic children, controlling for severity of asthma, and
comparing psychiatric outcomes in those who were treated
with a lot of steroids, vs. those receiving less, or none?
Might be enough variance in corticosteroid use for
decent statistical power. |
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[-]. If you're going to throw money at the problem, just improve the accommodations, don't pump the kids full of drugs. |
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What happened to "The Customer Is Always Right" ? Maybe the kids like the drugs ... |
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The customer is the one who *pays* [8th], not the one on
whom the product or service is inflicted. (So, I guess you've
never actually worked as a professional assasin, then?) |
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No, but we have worked as an Assassin. |
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// not the one on whom the product or service is inflicted // |
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Two words: "Network Rail". |
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Understandable: you don't want to lose your amateur status.
The product endorsement contracts are so lucrative. |
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I think the right word is "client." One of Gene Wolfe's more
inspired details was having professional torturers refer to
their victims that way. |
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// product endorsement contracts // |
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Actually, we do it for the fun, not the money. |
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// professional torturers refer to their victims that way. // |
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Network Rail also use the term "clients". Ipso facto, we rest our case. |
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