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I read that transplant doctors worry about infection because of immunosupressant drugs used on the patients.
I have not heard of a nozzle of purified air directed at the surgery site and the surgery theater generally to reduce germ load to 1/100 or 1/1000th the usual amount.
To make sure it works
they could do "surgery" on agar gel culture blobs and then develop a system with much less colony growth.
Environmental Controls in Operating Theaters
https://www.ncbi.nl...gov/pubmed/12090793
From 2002 [lurch, May 21 2018]
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My fluid dynamics imaginations would indicate to me that there would be eddies and flows would be that would be hard compute for. Even a heavy sterile gas would slop out creating inflows. |
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Maybe, [beanangel] like you indicated, a self reconstituting, clear gel medium that can be worked through. Might even hold back bleeding. Just peel it out when finished. |
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A high-volume airflow into the surgical area will tend to dry things
out substantially. Since a transplant operation (at least, the part on
the immunosuppressed patient) is mostly installation, the doc is
spending most of his time doing microsuturing - and that's not much
fun when all the delicate vessels are getting dry & crackly, and the
sutures are waving in the breeze. |
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I agree with [wjt] - eddies would make things worse. |
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In my lab, I regularly pour agar plates. I normally do it on
the open bench, and I get maybe 1 plate in 20 with a fungal
contaminant. Bacterial contamination is rare, because the
agar normally contains either one or two antibiotics; but
fungal spores are a reasonable proxy for bacteria. If I turn
on the aircon (which just circulates the air within the
room), my contamination rate goes up noticeably. |
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The air in operating theatres is generally almost sterile
anyway. Surgical-site infections tend to be picked up once
the patient leaves the OR. |
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Regretfully (all the more so because you managed to write
"in the air"), therefore, [-]. |
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The surgery could be performed at very low temperatures (to reduce evaporative drying) and near-vacuum, which would remove the air which transports the pathogens. |
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That's not a bad idea. Best of all, the freeze-drying of
patients would allow for much longer, more leisurely
operations. |
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We understand that such a freeze-drying process (well, the freezing part, anyway) was commonplace in the waiting rooms of many public hospitals and clinics in the U.K. during your 20th century. |
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We are, of course, relying on hearsay for this, as there were very few - if any - survivors. They tend to be the ones who escaped before receiving any attention from the medics. |
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Although there would be eddies of air, I thought the zero fungi/bacteria per 100 m^3 would be less than the ambient bacteria/fungi. With zero contaminants the eddies in the fresh air would not matter. |
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I think of it as a gentle exhalation of ultrapure air near the surgery sit. saying "nozzle" did not really communicate that. The gentle exhalation version might skip the drying effect, as could modifying the humidity. |
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Bacteria don't spend much time floating around - they're
generally sitting on surfaces, and the last thing you want to
do is stir them up. |
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If you really want a sterile environment, close all the doors,
windows and vents, turn off all heating and cooling, have
everyone hold their breath, and wait about 10min. All
airborne bacteria will have settled out. |
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As I mentioned, the air in an operating theatre is to all
intents sterile anyway. Surgical infections tend to be
acquired after the surgery. Another source of infection is
the patient's own microbiome, which can do unexpected
things after you slice someone open. |
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If you're going with "gentle", then Baked, see Link. |
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Generally a couple of inches of water of positive pressure, so that
any leaks in the OR are leaking out, not in; and enough airflow that
there's 12 to 20 complete air changes per hour. The duct filters are
placed in the ceiling, with outflow vents low on the walls - so
everything travels downwards, as they are naturally inclined to do. |
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Bun from me for the educational value. |
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