Deuterated insulin

Deuterium is less than a quarter a gram deuterated insulin is likely to have last much longer from the isotope effect

fully deuterating 20 milligrams of insulin which would be a bunch as its a medically active peptide would cost less than half a ¢

modern insulins are produced via genetically engineered cultured material solitary microorganisms have been bred to survive an all deuterium culture fluid Thus breeding a current insulin producing organism to survive a deuterium environment is likely

wikipedia says words rather like The rate of a reaction involving a C-H group is typically 6 to 10 times faster than the corresponding C-D group

the deuterated version lasts longer plus resists degradation maybe creating an oral insulin with GI tract region carrying polymers

as a multiunit peptide there is also the opportunity to deuterate just part of the structure

anyway I think it would make it have different pharmacodynamics which could be worth the deuterium at less than part of a ¢

Note I just read a review article that said a thing rather like there was a 1993 patent on using deuterium isotope effect with drugs I thought what about peptides they may resist degradation or become more orally available (there are orally available peptides this could make them an order of magnitude stronger perhaps even an oral insulin)