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In theory, every atom in the human body could be
accounted for.
Knowing the elemental composition and overall mass
gives
us amounts of each element. As we work out molecular
models of the molecules of in the human body and their
amounts, they can be ticked off the elemental
stocktake.
Crystalline and fabric materials such as bone and cell
walls
have to be modeled, quantified. Respiratory gases,
although transitory should not be too much of a problem.
Gut fauna and biological interlopers would pose big
accuracy deficiency. But continual research in these
areas
will keep supplying data.
If the count is done in a patchwork fashion, the only way
it
can be done, then areas that are not known, will have
big
discrepancies between modeled molecular numbers and
elements weighed.
Stoichiometry is well and truly an rock solid tool in
science
but with supercomputer modeling and statistical
analysis,
can it be taken to a whole new level to show us where
the
unknowns are hiding.
P prime prime
https://en.wikipedi...P%E2%80%B2%E2%80%B2 the reference [Ian Tindale] attempted to make, which caused his cephalic and colonic content to blend & vent [lurch, Apr 16 2017]
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Annotation:
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OK, so this is not about quantitative epistemology, but rather about ... um ... |
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Are your bathroom scales broken? |
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Are you proposing to analyze the chemical composition
of the human body solely by measuring its mass to
extreme accuracy and precision? |
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In patchwork, Yes. As a reference for all those molecular
pathway models in the computer. Large mass discrepancy
= something unknown, something to be investigated. |
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Ultimately all models are collectively communal, or so say
the searching equational centric physicists. |
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... or possibly a doughnut. |
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It'll be somebody's body but not everybody's body: like the
genome project was just really one person's DNA wasn't it?
and just a snapshot, I'm pretty sure my the atoms will have
mostly moved on down the sewer within a few years and
then been picked by an Albanian in a mushroom farm and
sold to you wtj. Still, useful information to gather. I'd like
to see where I end up |
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//the genome project was just really one person's DNA wasn't it? // Actually it wasn't. The first "complete" (except it wasn't, really) human genome reference sequence was an amalgam of cloned fragments from multiple individuals. |
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Thanks for the correction MB.. I wonder if that amalgam
person will ever be born |
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Well, one person in 2^30000, roughly, should be that amalgam. Sadly that's -E- on my calculator. |
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You might like looking at all the chemicals at a
spectroscopy plot. The height of each chemical, as well
as the area under each chemical's "curve" speak to what
you are asking. |
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Also, nuclear magnetic resonance imaging NMR (related
to MRI) could be improved to detect more kinds of atoms
more effectively. |
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Also, pragmatically, if you are willing to use rats or pigs
as model experimental animals their individual organs can
be connected to something like a heart-lung pumping and
oxygenating and nutrient machine permitting ultra high
resolution scanning of something the size of say a heart or
a gland or a brain for elemental and molecular
composition |
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/'envelope' or 'convex hull'/
Made up of a collection of areas of focused interest. |
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[Max] Wouldn't the random stuff between genes mess with
that calculation? |
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// The 'envelope' or 'convex hull'. That's what that'd be
called. // |
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That would hide the valleys in the spectrogram, which
are just as important as the peaks. |
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My computer was not willing to calculate that either,
but Wolfram|Alpha was: |
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430 050 467 682 338 953 460 003 719 728 316 579 187
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036 892 336 467 993 833 313 566 351 099 012 062 133
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305 262 357 999 304 049 578 253 805 867 435 072 383
872 118 239 392 509 532 576 937 965 747 681 037 411 189
244 456 427 767 218 969 226 659 923 736 338 685 936
365 229 374 852 506 760 977 484 949 718 096 704 779
139 202 025 385 886 007 539 531 005 659 537 317 072 283
913 313 695 763 253 184 409 898 181 120 428 466 758 352
325 450 311 576 982 995 045 335 286 929 880 973 682
790 673 015 037 574 198 678 081 581 095 988 135 833
790 694 215 909 |
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// Wouldn't the random stuff between genes mess with that calculation?// No, it's all just DNA. That's why DNA is so fantastically cool - everything is just a bitstream. When you die of cancer, it's a bitstream. If you have your father's nose or your mother's beard, it's a bitstream. If you're not an elm, it's a bitstream. If you get Ebloa, it's a bitstream. DNA does for biology what computers do for photos, music, 3D models and pornography. |
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So have I got this right? On the transcripted strand each
position has four posibilities so that 4 x 4 x 4 x 4 .. for
however many base pairs there are in the Human genome. -
the areas that have to be the same to make us human
creatures + the available variance of those areas.All
summing to 2 ^30000 approx. |
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//So have I got this right?// Not as such, alas. In fact, my 2^30000 was a vague sort of guesstimate, based on the assumption that haplotype blocks (chunks of human DNA that tend to remain intact during recombination across many generations) are about 100kb long, hence 30,000 of them in the genome; and suppose there are a couple of common haplotypes for each one. |
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Then again, I didn't reckon on the fact that humans are mostly diploid, so it's more than that. |
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[Ian] Do you have an under the sea, Jules Verne-ish problem
with your computer? |
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[MaxwellB] Even two individuals with equal zygote DNA
could be told apart
by
their pockets' of mutations as age takes hold on cell
divisions. The body can't repair that perfectly, surely. |
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Then again, that is on the otherside of the zygote .
My statement is two adult individuals can't have the exactly
same makeup of DNA. Too much complexity. |
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I just realized that that great big number I posted the
other day is odd, while claiming to be a power of two.
It's also only 9029 digits long, not 9031 (according to:
echo "[the number]" | sed "s/ //g" | wc). I think I
would
have noticed if I had dropped two at the end, given
that
I processed it with Python to add the spaces, and had
to
adjust my code to get the spaces in the right place
relative to
the end of the number. Therefore I blame W|A for
giving me the wrong answer. |
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//Even to zygote DNA equals could be told apart by their pockets of mutations as age takes hold on cell divisions. // I have very little idea what that sentence means but, yes. No two cells in your body have the same genome. The next revolution in genomics will appreciate this. The 50%+ of "genetic" disorders which don't appear to be inherited will come down to somatic variation. If you want an independent confirnation of this, I strongly suggest that you ask me again, when sober. |
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//two adult individuals can't have the exactly same makeup of DNA.// Well,yes, although I would subsitute "one" for "two". |
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A zygote base line DNA reading is almost needed to see
changes. That or a multi-point DNA biopsy with a full
sequencing. |
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At MaxCo, we are pioneering Whole Body Sequencing. With something like a kilo of DNA to start with, even Nanopore sequencing might give some useful data. |
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The person gets up and walks away, right? |
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081 581 095 988 135 833 790 694 215 909 |
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You quite sure about that 812? |
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Where's Wally without a wally. I was disappointed. |
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