h a l f b a k e r yCompound disinterest.
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Longevity happiness elixir
Immunizing against MAO-B could cause greater cheerfulness and immunize against depression, it could cause greater longevity as well. | |
Dperenyl, also known as the Esam patch, is an
antidepressant. It inhibits monoamine oxidase B (MAO-B).
[link].
Soaking up all the MAO-B another way could also be
anantidepressant. That suggests that immunizing against
MAO-B could cause greater cheerfulness and immunize
against depression
Deprenyl
causes four species of mammals to live 9-30%
longer! There is a possibility that immunizing against
monoamine oxidase B causes greater longevity as well.
If everything went right with an MAO-B immunization
then
one oral dose, once, could cause greater happiness and
greater longevity for a lifetime..
deprenyl the antidepressant at wikipedia
https://en.wikipedia.org/wiki/Selegiline
[beanangel, Oct 16 2018]
Deprenyl makes rats live 34% longer
https://www.ncbi.nl....gov/pubmed/8030852
[beanangel, Oct 16 2018]
An immunization against monoamine oxidase causes a ;earning effect
https://www.ncbi.nl....gov/pubmed/9809286
[beanangel, Oct 18 2018]
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Annotation:
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//immunizing against MAO-B// Well, you're going to have a
problem immunising against a normal human protein. Also, if
you managed it you'd (a) have a permanent autoimmune
disease and (b) would have a permanent MOA-B deficiency. If
you decided that it wasn't right for you, you'd basically be
fucked. |
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My joy at the return of the HB is lifted to new heights by my
ability to bone. |
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I never bone but it's tempting in this case. One thing
this does make me wonder about, though, is whether
depression has a biological function. |
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Here is what Wikipedia says: |
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"people lacking the gene for MAO-B display no abnormalities except elevated phenethylamine levels in urine, raising the question of whether MAO-B is actually a necessary enzyme." |
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Like others, I tend to doubt that the neurologic system is producing a completely uneccessary enzyme. |
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Addendum: before attempting this, perhaps someone should survey whether people who lack the gene for MAO-B are much happier than the general population, live much longer, feel drained of phenethylamine, etc. |
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[4and20] great idea! There are 2 records at pubmed about
MAO A and B gene deletion. It is really bad for people. |
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There remains optimism though, I would look to see if
different SNPs (gene variants) had any benefit. |
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I have heard of an idea that depression may in some cases
be adaptive, making it easier for the person to think about
what's causing problems in their life. I can't easily find any
mention of it in Wikipedia, though. |
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