With the obesity epidemic, many overweight men find themselves to be disturbingly buxom. It is one thing to have a manly paunch, but breasts are another matter entirely. Part of this phenomenon is due to the fact that adipose tissue generates estrogen. With estrogen comes a female pattern of fat deposition - and breasts begin to grow.
The aromatase inhibitors are a new class of drugs developed to treat breast cancer, which work by blocking all estrogen synthesis in the body. I propose that a daily dose of one of these drugs could prevent fatty tissue from synthesizing estrogen. The result: de-estrogenized men would deposit fat on the gut, where manfat belongs, leaving the chest flat and hairy. There may be other beneficial side effect to these estrogen blocking drugs, such as a greater appreciation for the Three Stooges.-- bungston, May 25 2004 Arimidex mechanism http://www.breastca...ic/moa/moa_arim.asp [bungston, Oct 04 2004, last modified Oct 06 2004] Gut barging http://www.tuttoben...nd/en/sports.htm#t3These guys would jump at the chance to buy the latest Bungco product... [spacemoggy, Oct 04 2004, last modified Oct 06 2004] Holy Homo Acinii ! http://xoomer.virgi...uereproductive.html... especially prominent mention under "pathology". [dpsyplc, Oct 04 2004, last modified Oct 06 2004] Or, put them to use? http://www.unassist...rth.com/milkmen.htm [Klaatu, Oct 04 2004, last modified Oct 06 2004] Brilliant idea! And I may have just found your most loyal customers. [link]-- spacemoggy, May 25 2004 I'll give you a croissant for calling men "buxom." And it's a good idea, to boot.
One note, though - it's not actually the adipose tissue that generates estrogen and its precursors - the body detects a higher level of fat in the body, and reacts by having the adrenal glands (ittybitty things on top of the kidneys) generate estrogen.
So while obesity causes estrogen production, it's not a direct link - there are some intermediaries.-- shapu, May 25 2004 3 stodges?-- po, May 25 2004 We call 'em "chap-paps" round here. Well, I do anyway.
Good idea, though. +1-- lostdog, May 25 2004 I mis-read this as Manboob Bustier. Something to enhance them.-- oneoffdave, May 26 2004 I liked Klaatu's link. I have renewed faith in being able to use the power of my mind to will my tummy fat into a nearby jam jar.-- benjamin, May 26 2004 This is perfect for SPAM mailing to people as an offer. Just like a the V1agAra spam I get, but of course, have no need for.-- macncheesy, May 27 2004 random, halfbakery